ADVENTURE GUIDE / BUILDS
Venomous Fangs poison build
A melee setup centered on Venomous Fangs’ poison attacks. Balance offensive and defensive support, adding area coverage when needed.
- Updated
Overview and reasons to try
Build melee offense around Venomous Fangs and Venomancer. Choose poison-oriented equipment separately from equipment supporting direct hits.
Poison Fog is an option for additional area coverage. Other enchantments are also worth considering when focusing on a single target.
Grindstone and Banner support offense, while Chimes remains the defensive option. Prioritize a safe retreat when health or souls run low.
- Choose equipment by its role in poison, direct attacks and defensive support.
- Poison Fog is optional, leaving room to choose healing support or area attacks.
12-position equipment layout
12 / 12 recommended positionsAdditional effects can differ between copies of an item. Choose enchantments to suit the way you play.
Melee weapon

Recommended equipment
Venomous FangsThe core melee weapon for poison attacks and Venomancer. Choose Poison Fog when you want additional area coverage.
Effects, enchantments and alternatives
The core melee weapon for poison attacks and Venomancer. Choose Poison Fog when you want additional area coverage.
Native effects
- Venomancer Unique
Poison attacks deal 20% more damage.
Enchantment candidates
- Healing Smite III — Recommended
An option for healing support on kills. Boss fights with few adds offer fewer healing opportunities.
Tier effect: Defeating an enemy has a 50% chance to create a Regenerating well for allies.
- Poison Fog III — Alternative
Poison Fog is an option for additional area coverage. Other enchantments are also worth considering when focusing on a single target.
Tier effect: Wave deals 30% of weapon damage and poisons mobs for a time.
Additional effects to look for
- Bounty Hunter III
Deal 30% more damage to wounded enemies.
- Intended synergy
- Additional effects vary between copies. Choose by the role you want to improve: offense, recovery, arrows, souls or defense.
Alternative candidates
Double Daggers
A base-dagger alternative, without treating it as the Fangs’ native poison-enhancing setup.
Enchantment candidates
- Healing Smite III — Recommended
An option for healing support on kills. Boss fights with few adds offer fewer healing opportunities.
Tier effect: Defeating an enemy has a 50% chance to create a Regenerating well for allies.
- Poison Fog III — Alternative
Poison Fog is an option for additional area coverage. Other enchantments are also worth considering when focusing on a single target.
Tier effect: Wave deals 30% of weapon damage and poisons mobs for a time.
Sift Sickles
A melee alternative focused on increased healing.
Native effects
- Healer Unique
Increases healing given to yourself and allies by 50%.
Enchantment candidates
- Healing Smite III — Recommended
An option for healing support on kills. Boss fights with few adds offer fewer healing opportunities.
Tier effect: Defeating an enemy has a 50% chance to create a Regenerating well for allies.
- Poison Fog III — Alternative
Poison Fog is an option for additional area coverage. Other enchantments are also worth considering when focusing on a single target.
Tier effect: Wave deals 30% of weapon damage and poisons mobs for a time.
Additional effects to look for
- Bounty Hunter III
Deal 30% more damage to wounded enemies.
- Venomancer Unique
Ranged weapon

Recommended equipment
Double CrossersA backup ranged weapon with support for attacks after rolling, for enemies that are difficult to approach.
Effects, enchantments and alternatives
A backup ranged weapon with support for attacks after rolling, for enemies that are difficult to approach.
Native effects
- Dynamo Unique
Rolling applies 50% damage amplification to your next melee or ranged attack.
- Ammo
- 20
Enchantment candidates
- Piercing III — Recommended
For support shooting against enemies lined up in a row.
Tier effect: Projectiles can pierce up to 5 enemies.
- Ricochet III — Optional
Choose it to bounce shots between multiple enemies. Other effects can suit fights with widely separated targets.
Tier effect: Projectiles can bounce up to 3 times.
Additional effects to look for
- Bounty Hunter III
Deal 30% more damage to wounded enemies.
- Intended synergy
- Additional effects vary between copies. Choose by the role you want to improve: offense, recovery, arrows, souls or defense.
Alternative candidates
Dual Crossbows
A base-item alternative chosen for the additional effects on the copy you own.
- Ammo
- 20
Enchantment candidates
- Piercing III — Recommended
For support shooting against enemies lined up in a row.
Tier effect: Projectiles can pierce up to 5 enemies.
- Ricochet III — Optional
Choose it to bounce shots between multiple enemies. Other effects can suit fights with widely separated targets.
Tier effect: Projectiles can bounce up to 3 times.
Additional effects to look for
- Bounty Hunter III
Deal 30% more damage to wounded enemies.
Harp Crossbow
An option for extra projectiles when shooting at groups of enemies.
Native effects
- Ranger Unique
Grants a 60% chance to fire additional projectiles.
- Ammo
- 12
Enchantment candidates
- Piercing III — Recommended
For support shooting against enemies lined up in a row.
Tier effect: Projectiles can pierce up to 5 enemies.
- Ricochet III — Optional
Choose it to bounce shots between multiple enemies. Other effects can suit fights with widely separated targets.
Tier effect: Projectiles can bounce up to 3 times.
- Dynamo Unique
Helmet

Recommended equipment
Fly Agaric CapA poison-oriented helmet with Venomancer.
Effects, enchantments and alternatives
A poison-oriented helmet with Venomancer.
Native effects
- Venomancer Unique
Poison attacks deal 20% more damage.
Enchantment candidates
- Power Amplifier III — Recommended
An option for a playstyle focused on attacking after artifact use.
Tier effect: After artifact use, the declared damage amplification parameter for the next melee or ranged attack is 40%. Stacking and final damage calculations remain unverified.
Additional effects to look for
- Venomancer III
Poison attacks deal 20% more damage.
- Intended synergy
- Additional effects vary between copies. Choose by the role you want to improve: offense, recovery, arrows, souls or defense.
Alternative candidates
Mushroom Cap
A base-helmet alternative whose role depends on its additional effects.
Enchantment candidates
- Power Amplifier III — Recommended
An option for a playstyle focused on attacking after artifact use.
Tier effect: After artifact use, the declared damage amplification parameter for the next melee or ranged attack is 40%. Stacking and final damage calculations remain unverified.
Additional effects to look for
- Venomancer III
Poison attacks deal 20% more damage.
Dauntless Horns
An alternative helmet focused on knockback.
Native effects
- Knockback Unique
Attacks do 40% more knockback.
Enchantment candidates
- Power Amplifier III — Recommended
An option for a playstyle focused on attacking after artifact use.
Tier effect: After artifact use, the declared damage amplification parameter for the next melee or ranged attack is 40%. Stacking and final damage calculations remain unverified.
- Venomancer Unique
Chestplate

Recommended equipment
Sage TunicA chestpiece focused on damage to wounded enemies. Consider defensive additional effects alongside offense.
Effects, enchantments and alternatives
A chestpiece focused on damage to wounded enemies. Consider defensive additional effects alongside offense.
Native effects
- Bounty Hunter Unique
Deal 40% more damage to wounded enemies.
Enchantment candidates
- Bottomless Brew III — Recommended
For a playstyle that uses potions often, alongside Ancient Alchemy’s soul support.
Tier effect: Grants 3 additional health potions.
Additional effects to look for
- Protection III
Take 20% less damage.
- Intended synergy
- Additional effects vary between copies. Choose by the role you want to improve: offense, recovery, arrows, souls or defense.
Alternative candidates
Fly Agaric Coat
An alternative focused on recovery after leaving combat.
Native effects
- Regeneration Unique
Restores health by 30% per second after 5 seconds out of combat.
Enchantment candidates
- Bottomless Brew III — Recommended
For a playstyle that uses potions often, alongside Ancient Alchemy’s soul support.
Tier effect: Grants 3 additional health potions.
Additional effects to look for
- Protection III
Take 20% less damage.
Dauntless Pauldrons
An alternative for reducing damage from ranged attacks.
Native effects
- Projectile Protection Unique
Take 25% less damage from ranged attacks.
Enchantment candidates
- Bottomless Brew III — Recommended
For a playstyle that uses potions often, alongside Ancient Alchemy’s soul support.
Tier effect: Grants 3 additional health potions.
Additional effects to look for
- Protection III
Take 20% less damage.
- Bounty Hunter Unique
Leggings

Recommended equipment
Dauntless GreavesLeg armor focused on the opening hit against full-health enemies, a different role from wounded-target bonuses.
Effects, enchantments and alternatives
Leg armor focused on the opening hit against full-health enemies, a different role from wounded-target bonuses.
Native effects
- Vanguard Unique
Deal 60% more damage to enemies who are at full health.
Enchantment candidates
- Ancient Alchemy III — Recommended
Soul replenishment when using potions, supporting artifact resource costs.
Tier effect: Potion usage grants 60 souls.
Additional effects to look for
- Protection III
Take 20% less damage.
- Intended synergy
- Additional effects vary between copies. Choose by the role you want to improve: offense, recovery, arrows, souls or defense.
Alternative candidates
Monarch Sash
An alternative leg armor for soul capacity.
Native effects
- Spiritual Unique
Increases Soul capacity by 50%.
Enchantment candidates
- Ancient Alchemy III — Recommended
Soul replenishment when using potions, supporting artifact resource costs.
Tier effect: Potion usage grants 60 souls.
Mad Sifter Slacks
An alternative leg armor focused on positive-status duration.
Native effects
- Boost Unique
Increases duration of positive statuses applied to you by 20%.
Enchantment candidates
- Ancient Alchemy III — Recommended
Soul replenishment when using potions, supporting artifact resource costs.
Tier effect: Potion usage grants 60 souls.
- Vanguard Unique
Boots

Recommended equipment
Monarch TalonsBoots focused on attacks against enemies affected by negative statuses.
Effects, enchantments and alternatives
Boots focused on attacks against enemies affected by negative statuses.
Native effects
- Bully Unique
Deal 50% more damage to enemies affected by a negative status.
Enchantment candidates
- Health Synergy III — Recommended
An option for healing when using artifacts.
Tier effect: Artifact usage heals 35% of your maximum health.
- Dynamo III — Optional
An alternative for a playstyle focused on attacks after rolling.
Tier effect: After a roll, the declared damage amplification parameter for the next melee or ranged attack is 40%. Stacking and final damage calculations remain unverified.
Additional effects to look for
- Venomancer III
Poison attacks deal 20% more damage.
- Intended synergy
- Additional effects vary between copies. Choose by the role you want to improve: offense, recovery, arrows, souls or defense.
Alternative candidates
Rimefrost Plodders
An alternative focused on the duration of negative statuses applied to enemies.
Native effects
- Tainted Unique
Increases duration of negative statuses on enemies by 100%.
Enchantment candidates
- Health Synergy III — Recommended
An option for healing when using artifacts.
Tier effect: Artifact usage heals 35% of your maximum health.
- Dynamo III — Optional
An alternative for a playstyle focused on attacks after rolling.
Tier effect: After a roll, the declared damage amplification parameter for the next melee or ranged attack is 40%. Stacking and final damage calculations remain unverified.
Additional effects to look for
- Venomancer III
Poison attacks deal 20% more damage.
Dauntless Sabatons
Boots that increase soul capacity, useful when storing souls for support artifacts.
Native effects
- Spiritual Unique
Increases Soul capacity by 50%.
Enchantment candidates
- Health Synergy III — Recommended
An option for healing when using artifacts.
Tier effect: Artifact usage heals 35% of your maximum health.
- Dynamo III — Optional
An alternative for a playstyle focused on attacks after rolling.
Tier effect: After a roll, the declared damage amplification parameter for the next melee or ranged attack is 40%. Stacking and final damage calculations remain unverified.
- Bully Unique
Artifact 1

Recommended equipment
GrindstoneAn artifact supporting melee attacks, for situations where direct hits matter.
Effects, enchantments and alternatives
An artifact supporting melee attacks, for situations where direct hits matter.
- Cooldown
- 4
- Cost
- 30
Additional effects to look for
- Venomancer III
Poison attacks deal 20% more damage.
- Cooldown III
Reduces artifact cooldown time by 20%.
- Intended synergy
- Additional effects vary between copies. Choose by the role you want to improve: offense, recovery, arrows, souls or defense.
Alternative candidates
Fighting Fungus
An alternative when choosing offensive support for a playstyle that includes melee.
- Cooldown
- 5
- Cost
- 20
Additional effects to look for
- Venomancer III
Poison attacks deal 20% more damage.
- Cooldown III
Reduces artifact cooldown time by 20%.
Electric Bangle
An offensive alternative for additional lightning. Keep Chimes when safer approaches matter more.
- Cooldown
- 6
- Cost
- 35
Additional effects to look for
- Venomancer III
Poison attacks deal 20% more damage.
- Cooldown III
Reduces artifact cooldown time by 20%.
Artifact 2

Recommended equipment
Battle BannerOffensive support for yourself and nearby allies when you can fight near the banner.
Effects, enchantments and alternatives
Offensive support for yourself and nearby allies when you can fight near the banner.
- Cooldown
- 10
- Cost
- 45
Additional effects to look for
- Venomancer III
Poison attacks deal 20% more damage.
- Ally III
Positive statuses you apply to yourself and allies last 50% longer.
- Intended synergy
- Additional effects vary between copies. Choose by the role you want to improve: offense, recovery, arrows, souls or defense.
Alternative candidates
Venomous Quiver
An option for adding poison to ranged shooting.
- Cooldown
- 5
- Cost
- 20
Additional effects to look for
- Venomancer III
Poison attacks deal 20% more damage.
Electric Bangle
An offensive alternative for additional lightning. Keep Chimes when safer approaches matter more.
- Cooldown
- 6
- Cost
- 35
Additional effects to look for
- Venomancer III
Poison attacks deal 20% more damage.
Artifact 3

Recommended equipment
Warding ChimesDefensive support for approaching enemies. Choose it over an offensive support when safety matters more.
Effects, enchantments and alternatives
Defensive support for approaching enemies. Choose it over an offensive support when safety matters more.
- Cooldown
- 15
- Cost
- 40
Additional effects to look for
- Venomancer III
Poison attacks deal 20% more damage.
- Spiritual III
Increases Soul capacity by 35%.
- Intended synergy
- Additional effects vary between copies. Choose by the role you want to improve: offense, recovery, arrows, souls or defense.
Alternative candidates
Electric Bangle
An offensive alternative for additional lightning. Keep Chimes when safer approaches matter more.
- Cooldown
- 6
- Cost
- 35
Additional effects to look for
- Venomancer III
Poison attacks deal 20% more damage.
- Spiritual III
Increases Soul capacity by 35%.
Venomous Quiver
An option for adding poison to ranged shooting.
- Cooldown
- 5
- Cost
- 20
Additional effects to look for
- Venomancer III
Poison attacks deal 20% more damage.
- Spiritual III
Increases Soul capacity by 35%.
Talisman 1

Recommended equipment
Thrifty PendantAn option for offense based on carried emeralds. Consider a healing alternative if you take frequent hits.
Effects, enchantments and alternatives
An option for offense based on carried emeralds. Consider a healing alternative if you take frequent hits.
Talisman level effects
Choose a level that suits the items you own.
Level 1
- Slinger of Bling I
Level 2
- Slinger of Bling II
Level 3
- Slinger of Bling III
- Intended synergy
- Additional effects vary between copies. Choose by the role you want to improve: offense, recovery, arrows, souls or defense.
Alternative candidates
Fist of Iron
An alternative talisman focused on melee attacks.
Talisman level effects
Choose a level that suits the items you own.
Level 1
- Sharpness I
Melee attacks deal 10% more damage.
Level 2
- Sharpness II
Melee attacks deal 20% more damage.
Level 3
- Sharpness III
Melee attacks deal 35% more damage.
Sigil of Beeswax
A defensive alternative that increases health.
Talisman level effects
Choose a level that suits the items you own.
Level 1
- Constitution I
Increases the player's maximum health by 20%.
Level 2
- Constitution II
Increases the player's maximum health by 25%.
Level 3
- Constitution III
Increases the player's maximum health by 35%.
Talisman 2

Recommended equipment
Tendrils of the SproutOffensive support for a playstyle that keeps health high. Switch to healing or health equipment when taking frequent hits.
Effects, enchantments and alternatives
Offensive support for a playstyle that keeps health high. Switch to healing or health equipment when taking frequent hits.
Talisman level effects
Choose a level that suits the items you own.
Level 1
- Healthy Strike I
Grants a 10% damage increase while health is above 95%.
Level 2
- Healthy Strike II
Grants a 20% damage increase while health is above 85%.
Level 3
- Healthy Strike III
Grants a 40% damage increase while health is above 75%.
- Intended synergy
- Additional effects vary between copies. Choose by the role you want to improve: offense, recovery, arrows, souls or defense.
Alternative candidates
Sigil of Beeswax
A defensive alternative that increases health.
Talisman level effects
Choose a level that suits the items you own.
Level 1
- Constitution I
Increases the player's maximum health by 20%.
Level 2
- Constitution II
Increases the player's maximum health by 25%.
Level 3
- Constitution III
Increases the player's maximum health by 35%.
Healing Heart
A healing-focused alternative to an offensive talisman.
Talisman level effects
Choose a level that suits the items you own.
Level 1
- Regeneration I
Restores health by 2% per second after 5 seconds out of combat.
Level 2
- Regeneration II
Restores health by 6% per second after 5 seconds out of combat.
Level 3
- Regeneration III
Restores health by 10% per second after 5 seconds out of combat.
- Healthy Strike I
Talisman 3

Recommended equipment
Twisted ToothA talisman for soul gathering. Capacity or healing options can suit fights with few gathering opportunities.
Effects, enchantments and alternatives
A talisman for soul gathering. Capacity or healing options can suit fights with few gathering opportunities.
Talisman level effects
Choose a level that suits the items you own.
Level 1
- SoulGather_TalismanEffect I
Increases souls gained by 40%.
Level 2
- SoulGather_TalismanEffect II
Increases souls gained by 80%.
Level 3
- SoulGather_TalismanEffect III
Increases souls gained by 140%.
- Intended synergy
- Additional effects vary between copies. Choose by the role you want to improve: offense, recovery, arrows, souls or defense.
Alternative candidates
Essence of Efficiency
An alternative for artifact cooldowns. Keep resource consumption in mind.
Talisman level effects
Choose a level that suits the items you own.
Level 1
- Cooldown I
Reduces artifact cooldown time by 4%.
Level 2
- Cooldown II
Reduces artifact cooldown time by 8%.
Level 3
- Cooldown III
Reduces artifact cooldown time by 14%.
Soul Chip
An alternative for storing more souls. Capacity and gathering serve different roles.
Talisman level effects
Choose a level that suits the items you own.
Level 1
- Spiritual I
Increases Soul capacity by 15%.
Level 2
- Spiritual II
Increases Soul capacity by 20%.
Level 3
- Spiritual III
Increases Soul capacity by 35%.
- SoulGather_TalismanEffect I
Key enchantments and reasons
The equipment details list enchantments for different playstyles. Choose replacements by the role they serve.

Healing Smite
An option for healing support on kills. Boss fights with few adds offer fewer healing opportunities.

Poison Fog
Poison Fog is an option for additional area coverage. Other enchantments are also worth considering when focusing on a single target.

Piercing
For support shooting against enemies lined up in a row.

Ricochet
Choose it to bounce shots between multiple enemies. Other effects can suit fights with widely separated targets.

Power Amplifier
An option for a playstyle focused on attacking after artifact use.

Bottomless Brew
For a playstyle that uses potions often, alongside Ancient Alchemy’s soul support.

Ancient Alchemy
Soul replenishment when using potions, supporting artifact resource costs.

Health Synergy
An option for healing when using artifacts.

Dynamo
An alternative for a playstyle focused on attacks after rolling.
Effects this setup focuses on
- Poison damage
See each position for native effects, additional roll targets and enchantments.
Choosing equipment for the situation
Choosing between Poison Fog and healing
Poison Fog adds a wave-based area attack. It is not mandatory for a poison-oriented setup.
Healing Smite is another option for support from kills. Boss fights with few adds offer fewer opportunities for kill-triggered healing.
Offensive alternatives
Electric Bangle can replace Chimes when you want additional lightning. This removes defensive support during approaches.
Fist of Iron is a melee-focused talisman alternative. Do not treat poison, melee and lightning bonuses as one shared multiplier; choose by the effects each item targets.
Survival alternatives
Keep Chimes and consider Sigil of Beeswax or Healing Heart for health and recovery.
Monarch Sash and Soul Chip are capacity alternatives. Capacity differs from gathering, so watch remaining souls during extended support use.
Armor for health and status conditions
Dauntless Greaves focuses on opening hits against full-health enemies, while Sage Tunic focuses on attacks against wounded enemies.
Monarch Talons focuses on attacks against enemies with negative statuses; Rimefrost Plodders focuses on negative-status duration.
How to play
- Check health, souls and artifact cooldowns before approaching.
- Use poison-type melee attacks and retreat before being surrounded. Choose Poison Fog when you want additional area coverage against groups.
- Avoid repeated support use as souls run low, mixing in shooting and evasion. Use the backup ranged weapon against difficult approaches.
Strengths and limitations
Strengths
- Fights that allow you to retreat after melee attacks.
- Situations that call for switching between poison, direct hits and support shooting.
Limitations
- Difficult approaches and terrain with few escape routes require care.
- Health-conditioned offensive support is harder to use when taking frequent hits.
Alternative equipment
Open each position for alternatives. If taking frequent hits, leave room for health, recovery and defensive support instead of focusing only on offense.